"Take responsible for YOUR OWN body, mind, and spirit, for your own physical, mental, and spiritual well being."

Mr. C.S. Haymore

I think this means that however you choose to live it is your responsibility. Whether that be a life of drug use it changes you physically, mentally, and spiritually being. This quote is also telling you to keep responsibility for your body and live a nice healthy lifestyle. 

Keeping your overall well being intact you must take of yourself. If not you won't live a good healthy lifestyle.